Mesotherapy has evolved considerably since its introduction in the 1950s. Today, different techniques may be used to deliver selected products to the skin, including traditional intradermal injections and microneedling-assisted topical application.
Mesotherapy was developed in France in the 1950s and traditionally refers to the administration of small quantities of selected substances through multiple superficial injections into the skin.
Originally developed for medical applications, the technique later became widely used in dermatology and aesthetic medicine. Today, the term mesotherapy is also used in aesthetic practice for the topical delivery of products in combination with microneedling.
Dr Michel Pistor introduces mesotherapy in France.
Different techniques may be used, including injections and microneedling-assisted topical application.
Dermapen is a microneedling device that creates multiple controlled microscopic channels in the skin. When combined with appropriately selected products, the treatment may have two complementary components.
The controlled micro-injuries created by microneedling activate the skin's natural repair response, which can support collagen and elastin production and improve skin texture.
The microscopic channels temporarily increase skin permeability and can facilitate the penetration of selected topical products. The degree of delivery depends on factors such as needle depth and the characteristics of the product used.
Products used or marketed for mesotherapy may have different intended routes of administration. A product suitable for topical application or microneedling-assisted application should not automatically be considered suitable for injection.
For injected mesotherapy, the product's authorized route of administration and its suitability for the intended treatment need to be considered.
International consensus recommendations advise the use of injectable products for mesotherapy and recognize that using a product through a route for which it is not authorized constitutes off-label use.
Depending on the skin assessment and selected technique, treatment may be considered for:
— Not every concern requires mesotherapy, and the appropriate treatment depends on the condition being treated. —
Your skin is examined and the technique and product are selected according to your concerns.
The skin is cleansed and prepared.
Microneedling is performed at an appropriate depth. Selected products may be applied according to their intended route of use.
Soothing care is applied and you will receive post-treatment advice.
Helpful answers to common questions about Mesotherapy and Dermapen treatment.
Traditional mesotherapy uses multiple superficial injections, while Dermapen is a microneedling device that creates controlled microscopic channels in the skin. Selected topical products may be used with Dermapen when appropriate.
Traditionally, mesotherapy refers to intradermal microinjections. In aesthetic practice, the term is also commonly used for selected topical products applied in combination with microneedling.
Mesotherapy products may have different intended routes of use. A product suitable for topical application or microneedling should not automatically be considered suitable for injection. The intended route should always be checked before treatment.
Dermapen provides controlled mechanical stimulation that supports the skin-remodelling response. The microscopic channels can also facilitate penetration of appropriately selected topical products.
Mild redness and sensitivity may occur after Dermapen and generally settle progressively. Downtime varies with treatment depth, the area treated and individual skin response.
Suitability depends on the skin condition and medical history. Active infection, significant inflammation or certain skin conditions may require treatment to be postponed or avoided.
Find out if Mesotherapy or Dermapen is suitable for your skin or hair concerns.
